Protein Structure · Steinegger Lab
MMseqs2-accelerated AlphaFold2 — the fastest route to an MSA-quality fold.
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30s–5min
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About this model
ColabFold replaces AlphaFold2's slow Jackhmmer search with MMseqs2, cutting alignment time from hours to seconds while preserving accuracy. It is the pragmatic default when you need MSA-grade predictions on more than a handful of sequences.
Standardized I/O contract
Every model in the Hub speaks the same contract, which is what lets the Router and the agent call any of them without special-casing.
Inputs
Protein sequence
Outputs
All-atom coordinates in PDB format, viewable and downloadable.
pLDDT score per residue (0–100). Above 70 is generally reliable.
