Antibody & Biologics · Ruffolo et al., Johns Hopkins
Antibody structure prediction ~1000× faster than AlphaFold2.
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1–30s
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About this model
IgFold exploits the fact that antibodies share a conserved framework: it only really has to predict the CDR loops. The result is sub-second structure prediction accurate enough for downstream docking and developability work.
Standardized I/O contract
Every model in the Hub speaks the same contract, which is what lets the Router and the agent call any of them without special-casing.
Inputs
Heavy chain
Light chain
Outputs
All-atom coordinates in PDB format, viewable and downloadable.
pLDDT score per residue (0–100). Above 70 is generally reliable.
