Data repository · Database
Gene Expression Omnibus
A public functional genomics archive for gene expression and DNA methylation profiling datasets.
What Gene Expression Omnibus is
Gene Expression Omnibus (GEO) is a repository for functional genomics records maintained by the National Center for Biotechnology Information (NCBI). It archives high-throughput screening data, primarily focused on gene expression profiling and DNA methylation profiling.
The repository stores data derived from microarray and RNA sequencing (RNA-Seq) experiments. To support consistency and reproducibility, data submitted to the resource conform to the Minimum Information About a Microarray Experiment (MIAME) format.
How it is organised
The archive stores records organised as expression series, experimental platforms, and curated datasets. Submitted high-throughput genomics data must adhere to the MIAME standard to ensure essential experimental context is captured alongside microarray or RNA-Seq measurements.
Key facts
- Managing organisation
- National Center for Biotechnology Information (NCBI)
- Repository category
- Repository
- Data types
- Microarray and RNA-Seq data
- Standards compliance
- Minimum Information About a Microarray Experiment (MIAME)
What you can use it for
- Gene expression profiling
- Retrieving and analysing high-throughput gene expression datasets derived from RNA-Seq or microarray experiments.
- DNA methylation analysis
- Accessing functional genomics datasets to investigate genomic DNA methylation profiles.
Query it here
The research agent queries Gene Expression Omnibus directly — no account, no API key — and every answer links back to the record it came from. Ask in plain language and it writes the query.
Strengths and limits
Good at
- Requires submitted data to conform to the MIAME format for consistent experimental descriptions.
Watch out for
- Genomics submissions must conform strictly to the MIAME format, which is required for experimental reporting.
Questions
Can I search Gene Expression Omnibus without writing code?
Yes. The research agent queries Gene Expression Omnibus directly, with no account or API key, and cites the record behind every answer. Ask in plain language — for a gene, a protein, a compound or a study — and it builds the query for you.
Can I reuse data from Gene Expression Omnibus?
Public submissions, free to use; some records carry submitter conditions. Terms: https://www.ncbi.nlm.nih.gov/geo/info/disclaimer.html
What organisation maintains the Gene Expression Omnibus?
The database is maintained and managed by the National Center for Biotechnology Information (NCBI).
What kinds of experimental data does the archive contain?
The archive holds high-throughput functional genomics screening data from microarray and RNA-Seq experiments, specifically focusing on gene expression and DNA methylation profiling.
What data standard is used for submissions?
Submissions must conform to the Minimum Information About a Microarray Experiment (MIAME) format.
Written from Gene Expression Omnibus's own website and reference material. Statements citing a figure that does not appear there are removed before publication. Licence and running details come from our registry.