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Genomics · Database

MGnify Human Gut (UHGG)

Metagenome-assembled and isolate genomes from the human gastrointestinal tract, clustered into species representatives with a matching protein catalogue.

What MGnify Human Gut (UHGG) is

MGnify Human Gut (UHGG) is a genomics resource maintained by MGnify at the European Bioinformatics Institute (EBI). It provides a comprehensive reference set of microbial genomes sourced from the human gastrointestinal tract.

It also includes an aligned protein catalogue to support researchers investigating the taxonomic and functional landscape of the human gut microbiome.

How it is organised

Genomic data from the human gastrointestinal tract—consisting of both isolate genomes and metagenome-assembled genomes—are clustered into species representatives. Alongside these clustered genomes, the resource provides an associated catalogue of matching protein sequences.

Key facts

Category
Genomics
Target environment
Human gastrointestinal tract
Content types
Isolate genomes, metagenome-assembled genomes, and a matching protein catalogue

What you can use it for

Protein catalogue interrogation
Scientists can query the matching protein catalogue to study the functional and metabolic potential of human gut microbial communities.
Comparative genomics between isolates and metagenome-assembled genomes
Investigators can compare cultured gut isolates with uncultured metagenome-assembled genomes across species-level clusters.

Query it here

The research agent queries MGnify Human Gut (UHGG) directly — no account, no API key — and every answer links back to the record it came from. Ask in plain language and it writes the query.

Strengths and limits

Good at

  • Integrates both laboratory isolate genomes and metagenome-assembled genomes from the human gastrointestinal tract.
  • Supplies a matching protein catalogue alongside representative genome assemblies.

Questions

Can I search MGnify Human Gut (UHGG) without writing code?

Yes. The research agent queries MGnify Human Gut (UHGG) directly, with no account or API key, and cites the record behind every answer. Ask in plain language — for a gene, a protein, a compound or a study — and it builds the query for you.

Can I reuse data from MGnify Human Gut (UHGG)?

CC0 1.0 / EMBL-EBI terms of use. Terms: https://www.ebi.ac.uk/about/terms-of-use

Does the database include both cultured and uncultured microorganisms?

Yes, it incorporates both isolate genomes from cultured strains and metagenome-assembled genomes recovered directly from gut metagenomic samples.

Who provides and maintains this catalogue?

It is maintained as part of the MGnify resource at the European Bioinformatics Institute (EBI).

Written from MGnify Human Gut (UHGG)'s own website and reference material. Statements citing a figure that does not appear there are removed before publication. Licence and running details come from our registry.