Single-Cell Perturbation · arcinstitute
Replogle-Nadig-Preprint
Perturb-seq single-cell perturbation dataset for perturbation-response modelling.
What Replogle-Nadig-Preprint is
Replogle-Nadig-Preprint is a single-cell perturbation dataset released by Arc Institute. It provides Perturb-seq screen data focused on applications across biology, genomics, and medicine.
The dataset was prepared and applied in the STATE single-cell embedding research to support the evaluation and training of perturbation-response models.
How it was made
The dataset consists of Perturb-seq experimental screens compiled for use in single-cell perturbation-response modelling and representation learning workflows.
Key facts
- Publisher
- Arc Institute
- Category
- Single-Cell Perturbation
- Fields
- Biology, genomics, medicine
- Application
- STATE single-cell embedding work
- Release date
- 2025-08-22
What you can use it for
- Perturbation-response modelling
- Train and evaluate computational models that predict single-cell transcriptional shifts following cellular perturbations.
- Single-cell embedding evaluation
- Benchmark single-cell representation architectures, such as STATE, using standardised Perturb-seq measurements.
- Genomic screen analysis
- Study cellular responses to genetic interventions across biological and medical research contexts.
Explore the data
No licence declared
The authors have not published a licence, which means no permission to redistribute the data has been granted to anyone. The rows are not served here; read them on the original dataset page.Strengths and limits
Good at
- Provides Perturb-seq data tailored for perturbation-response modelling.
- Directly compatible with research workflows developing the STATE single-cell embedding framework.
Watch out for
- Public summary details do not specify the exact gene targets, cell lines, or library sizes included in the preprint release.
- Validation data are oriented around the STATE single-cell embedding project rather than broader assay types.
Questions
Can I look inside Replogle-Nadig-Preprint without downloading it?
Not here: it declares no licence, so no permission to redistribute its rows has been granted. Its description and statistics are still shown.
What licence is Replogle-Nadig-Preprint under?
Its authors have not declared a licence, which means no permission to reuse or redistribute it has been granted.
What assay type is included in this dataset?
It contains Perturb-seq experimental screens, which combine pooled genetic perturbations with single-cell RNA sequencing.
What machine learning framework uses this dataset?
The data were used in the development and evaluation of the STATE single-cell embedding framework.
Which research areas does the dataset target?
It is designed for computational and experimental researchers in biology, genomics, and medicine.
Written from Replogle-Nadig-Preprint's own dataset card. Statements citing a figure that does not appear there are removed before publication. Licence and running details come from our registry.