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SettingsResearch demo · not for clinical or commercial use
Corollary
  1. Catalog
  2. Antibody & Biologics
  3. AntiFold

Antibody & Biologics · Hummer et al., DTU

AntiFold

Inverse folding specialised for antibody backbones and CDR loops.

Commercial use permittedThe BSD-3-Clause licence allows use in commercial research and products.BSD-3-Clause
Availability
On demand
Typical latency
5.0s
Credits per run
~28
Compute tier
A · Fast

1–30s

Runs on On-demand GPU

Runs on our servers with on-demand compute. A first run needs time to load the model; active capacity can be reused and scales down when idle.

Run this model

AntiFold

Needs antibody structure (pdb)

About this model

ProteinMPNN struggles with CDR loops because they are structurally atypical. AntiFold is trained on antibody structures specifically, and produces CDR sequences that respect the canonical framework.

Standardized I/O contract

Every model in the Hub speaks the same contract, which is what lets the Router and the agent call any of them without special-casing.

Inputs

  • pdbtextarea · required

    Antibody structure (PDB)

  • regionstext

    Regions to redesign

  • num_sequencesnumber

    How many designs

Outputs

  • sequencestable

    Redesigned regions with per-position log-odds.

Specification

Hardware
1× A100 16GB
GPU memory
8 GB
Version
1.0
Licence
BSD-3-Clause
Backend
On demandOn-demand GPU
MCP server
mcp-antibody-server

Tasks

inverse foldingcdr design
antibodyinverse-foldingcdr