Multi-Modal Foundation · living-models
Botanic0-M
A mid-sized plant genomic foundation model for regulatory annotation, expression inference, and variant effect analysis.
What Botanic0-M is
Botanic0-M is a plant genomic foundation model developed by living-models. It is a mid-sized model in the Botanic0 series designed for genomic research in plants.
The model is built to address downstream plant biology tasks, specifically the annotation of regulatory elements, the inference of gene expression, and the prediction of variant effects across plant genomes.
How it works
The model uses a transformer architecture consisting of 10 layers. It is trained on a genomic corpus composed of 43 plant genomes.
Key facts
- Architecture
- 10-layer transformer
- Model category
- Plant genomic foundation model
- Training data
- 43-genome plant corpus
- Release date
- 18 February 2026
What you can use it for
- Regulatory element annotation
- Annotating regulatory elements within plant genomic sequences.
- Gene expression inference
- Inferring gene expression profiles directly from plant genomic sequence data.
- Variant effect prediction
- Evaluating the functional impact of genetic variants across plant genomes.
Run it here
We list this model but cannot run it yet: gated on the Hub — never run past a gate the user did not accept.
Everything on this page still applies. Running it needs a loader for this repository, not a bigger machine.
Strengths and limits
Good at
- Pre-trained across a broad dataset encompassing 43 plant genomes.
- Configured to support multiple genomic tasks including regulatory annotation, expression inference, and variant evaluation.
Inputs and outputs
You provide
Sequence or text
A protein or nucleotide sequence, or free text — whichever this model was trained on.
You get back
Mean-pooled representation, one vector per input.
Licence
Check the licence before commercial use · other
This model is gated by its authors — its licence has to be accepted on the source repository before it will run.
Questions
Can I use Botanic0-M commercially?
Check the licence before commercial use. This model is gated by its authors — its licence has to be accepted on the source repository before it will run.
What is Botanic0-M?
Botanic0-M is a mid-sized plant genomic foundation model developed by living-models for biological and genomic research.
How many transformer layers does the model have?
Botanic0-M contains 10 transformer layers.
What training dataset was used for Botanic0-M?
It was trained on a 43-genome plant corpus.
What biological tasks is Botanic0-M trained to perform?
The model is trained for regulatory element annotation, gene expression inference, and variant effect prediction.
Written from Botanic0-M's own documentation (model card). Statements citing a figure that does not appear there are removed before publication. Licence and running details come from our registry.