Demonstration only. Corollary is a non-commercial research demo — no warranty, no support, not for commercial use or clinical decisions. Read the disclaimer

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Corollary vs AlphaFold Server

AlphaFold Server is Google DeepMind's free web service for AlphaFold 3, for non-commercial use with a daily job limit. Corollary does not run AlphaFold 3; it runs open models of the same kind, such as Boltz-2 and Chai-1, inside a free research agent.

The short answer

AlphaFold Server runs AlphaFold 3: proteins with DNA, RNA, ligands, ions and modifications, predicted together. It is for non-commercial use by individuals and non-commercial organisations, with a daily job limit, and its terms bar using the predictions in docking or other binding-prediction tools, or to train structure models.

Corollary does not run AlphaFold 3. It runs open models of the same kind — Boltz-2 and Chai-1 for complexes, ESMFold for single chains — through a research agent that prepares the inputs, reads the confidence back and carries on with the analysis. It is free, and a non-commercial research demonstration.

Choose AlphaFold Server for AlphaFold 3 itself. Choose Corollary when you want an open model whose licence lets you dock the result, or a prediction as one step of a wider analysis.

Side by side

What it is
CorollaryA research agent with a Linux machine of its own, and a library of open scientific models, programs, databases and pipelines it runs for you.
AlphaFold ServerA free web service for AlphaFold 3: structure prediction of proteins with DNA, RNA, ligands, ions and modifications.[1][2]
How you use it
CorollaryIn the browser, with a free account or signed out. Nothing to install. Also a developer API and an MCP server.
AlphaFold ServerIn the browser with a Google account, for individuals and non-commercial organisations. Commercial organisations are excluded, even for non-commercial work.[3][4]
Price
CorollaryFree. 30,000 credits a month with an account, 1,000 signed out; database queries never use credits.
AlphaFold ServerFree, with 30 jobs a day and up to 5,000 tokens a job.[2]
Commercial use
CorollaryNot permitted. Corollary is a non-commercial research demonstration, with no warranty or support.
AlphaFold ServerNon-commercial only. Outputs may not be used in automated binding-prediction tools such as docking, or to train structure models. Commercial AlphaFold 3 is offered through Google Cloud.[3][5][9]
Programs and pipelines
Corollary43 bioinformatics programs installed or run as jobs, and 143 nf-core pipelines.
AlphaFold ServerStructure prediction only, with custom MSAs and templates.[2]
Databases
Corollary53 public databases queried live, with no API key of your own.
AlphaFold ServerNot a database service.
Language model
CorollaryChosen and paid for by Corollary. No API key of your own.
AlphaFold ServerNone: no agent or language model.
Open source
CorollaryNo. The service is closed source; the models, programs and pipelines it runs are open.
AlphaFold ServerThe service is closed. AlphaFold 3's code is Apache-2.0; its weights are for non-commercial use and may not be redistributed.[7][8]
Your files
CorollaryUploaded to our servers and kept in the conversation's workspace. Some of our processors are in the United States.
AlphaFold ServerGoogle may keep time-stamped records of your inputs and outputs, even after you delete your account.[6]

AlphaFold Server's column is from its own public pages, read on 24 October 2026; the numbers link to them below. Corollary's figures are counted from the platform itself and each one links to the page that lists them.

Where AlphaFold Server is the better choice

  • AlphaFold 3 itself, from the team that built it, with several samples per seed and full confidence outputs.[2]
  • Complexes of proteins with DNA, RNA, ligands, ions, glycans and modifications in one prediction.[2]
  • Free, with 30 jobs a day.[2]
  • Custom MSAs and templates, and batch upload of jobs.[2]

Where Corollary is the better choice

  • Open models of the same kind — Boltz-2 and Chai-1 for complexes, ESMFold for single chains — run here on the free plan.
  • Boltz-2 and ESMFold are MIT-licensed, so their predictions can go straight into docking.
  • The agent does the work around the prediction: it prepares the inputs, reads the confidence back, compares predictions and carries on with the analysis.
  • More than structures: 43 bioinformatics programs and 53 public databases in the same conversation.

Try the same work on Corollary

Ask in plain language. The agent works on a Linux machine of its own: it installs and runs what the job needs, keeps every file, and reads the results back with the numbers explained.

Questions

Is Corollary a free alternative to AlphaFold Server?

Corollary is free: 30,000 credits a month with an account, and database queries never use credits. It is a non-commercial research demonstration, so it is not an alternative for commercial work — for that, AlphaFold Server or one of the other options below may be the right choice.

Is AlphaFold 3 free to use?

On AlphaFold Server, yes, for non-commercial use by individuals and non-commercial organisations, with a daily job limit. The weights for running it yourself are also for non-commercial use only. Commercial use goes through Google Cloud.

What are the alternatives to AlphaFold 3?

Open co-folding models such as Boltz-2 and Chai-1 predict complexes of proteins with ligands and nucleic acids, and Boltz-2 is MIT-licensed. Both run on Corollary from the browser, alongside ESMFold for single chains.

Sources

  1. [1]AlphaFold Server — about
  2. [2]AlphaFold Server — FAQ
  3. [3]AlphaFold Server — terms of service
  4. [4]AlphaFold Server — prohibited use
  5. [5]AlphaFold Server — output terms
  6. [6]AlphaFold Server — privacy
  7. [7]AlphaFold 3 — README (GitHub)
  8. [8]AlphaFold 3 — weights terms of use (GitHub)
  9. [9]Google Cloud — AlphaFold 3

Written by Corollary Labs, which makes Corollary — read it with that in mind. Everything said about AlphaFold Server comes from the sources above as they read on 24 October 2026; products change, and if a line here is out of date, write to hello@corollary-labs.com and we will correct it. AlphaFold Server and the other names here are trademarks of their owners, used only to identify their products. Corollary is a non-commercial research demonstrator. It is provided free of charge, without warranty or support, and must not be used for commercial purposes or relied upon for clinical, diagnostic, regulatory or safety-critical decisions.

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