Compare · AI research agents
Corollary vs Claude Science
Claude Science is Anthropic's desktop workbench for scientists: it runs on your computer, uses the compute you connect and comes with paid Claude plans. Corollary runs in the browser, on its own machines, free for non-commercial research.
The short answer
Claude Science is an app you install. Claude works in a sandbox on your computer, or on a Linux server you set up, and reaches GPUs through hardware and accounts you connect: your own machine, a Slurm cluster, Modal, or NVIDIA's hosted models. It comes with paid Claude plans from Pro upwards, and is in public beta.
Corollary is a hosted service. The agent has a Linux machine of its own on our servers, and 145 open models run here, so nothing needs installing or connecting. It is free, and it is a non-commercial research demonstration.
Choose Claude Science if your data must stay on your own computer, if you already have a cluster or a GPU budget, or if you need commercial terms. Choose Corollary to have structure prediction, protein design and pipelines working in a browser today, without hardware or a subscription.
Side by side
- What it is
- CorollaryA research agent with a Linux machine of its own, and a library of open scientific models, programs, databases and pipelines it runs for you.
- Claude ScienceAnthropic's AI workbench for scientists: a desktop app in which Claude analyses data, runs code and produces figures and documents that keep their provenance.[2]
- How you use it
- CorollaryIn the browser, with a free account or signed out. Nothing to install. Also a developer API and an MCP server.
- Claude ScienceA desktop app for macOS, Windows and Linux, or installed on a remote Linux server. It needs a Claude Pro, Max, Team or Enterprise plan.[3][17]
- Price
- CorollaryFree. 30,000 credits a month with an account, 1,000 signed out; database queries never use credits.
- Claude ScienceIncluded in Claude plans from Pro, at $20 a month ($17 billed annually); not on the free plan. Compute is extra and billed by whoever provides it.[4][3][5]
- Commercial use
- CorollaryNot permitted. Corollary is a non-commercial research demonstration, with no warranty or support.
- Claude SciencePermitted. Team and Enterprise plans fall under Anthropic's commercial terms.[9]
- Where the work runs
- CorollaryOn our servers: a Linux machine per conversation, and jobs of up to 32 cores, 256 GiB of memory and 24 hours for long runs.
- Claude ScienceOn your own computer, in a sandbox. Anthropic provides no compute: GPUs come from your own Linux machine, an SSH or Slurm cluster, your own Modal account, or NVIDIA's hosted models with your own key.[7][5]
- Scientific AI models
- Corollary301 models in the library, 145 of them run here — GPU included, with no setup and no key of your own.
- Claude ScienceSkills for AlphaFold2, Boltz-2, Chai-1, ESMFold2, OpenFold3, ProteinMPNN, DiffDock, Evo 2 and others, run on the hardware you connect.[8][5]
- Programs and pipelines
- Corollary43 bioinformatics programs installed or run as jobs, and 143 nf-core pipelines.
- Claude SciencePython, R and shell, with packages from conda-forge, bioconda, PyPI, CRAN and Bioconductor, and no root access. Long jobs go to your own cluster through Slurm.[6][15]
- Databases
- Corollary53 public databases queried live, with no API key of your own.
- Claude ScienceMore than 60 scientific databases through connectors, plus any MCP server you add.[1][16]
- Language model
- CorollaryChosen and paid for by Corollary. No API key of your own.
- Claude ScienceClaude — the models your plan includes.[1]
- Open source
- CorollaryNo. The service is closed source; the models, programs and pipelines it runs are open.
- Claude ScienceNo.
- Your files
- CorollaryUploaded to our servers and kept in the conversation's workspace. Some of our processors are in the United States.
- Claude ScienceProjects stay on the computer running the app, with no cloud copy; prompts and the file contents Claude reads go to Anthropic. Not covered by Anthropic's BAA, so no protected health information.[11][9][10]
Claude Science's column is from its own public pages, read on 24 October 2026; the numbers link to them below. Corollary's figures are counted from the platform itself and each one links to the page that lists them.
Where Claude Science is the better choice
- Your files stay on your own computer, and the code runs in a sandbox there — useful when data may not leave your institution.[7][11]
- It uses compute you already have: your own GPU, your cluster through SSH and Slurm, or your Modal account.[5]
- Commercial use is allowed, with enterprise controls such as SSO and SCIM.[1]
- Every result keeps the messages, code, execution log and environment that produced it, and a reviewer checks claims against that record.[14][13]
- It is not limited to biology: chemistry, physics, materials, mathematics and the social sciences are in scope.[3]
- Academic and nonprofit PIs can get Team seats at no cost for 12 months, while places last.[12]
Where Corollary is the better choice
- Free, with no subscription: 30,000 credits a month, and database queries never use credits.
- No hardware to bring: 145 models — structure prediction, protein design, docking, genomics — run here, with no cluster, Modal account or NVIDIA key of your own.
- Nothing to install: it runs in a browser, and long jobs keep running after you close the page or your laptop.
- 143 nf-core pipelines run as jobs on machines of their own, without a cluster.
Try the same work on Corollary
Ask in plain language. The agent works on a Linux machine of its own: it installs and runs what the job needs, keeps every file, and reads the results back with the numbers explained.
Questions
Is Corollary a free alternative to Claude Science?
Corollary is free: 30,000 credits a month with an account, and database queries never use credits. It is a non-commercial research demonstration, so it is not an alternative for commercial work — for that, Claude Science or one of the other options below may be the right choice.
Do I need a GPU to use Claude Science?
Not for the app itself. To run models such as AlphaFold2 or Boltz-2 it needs compute you connect: a Linux machine with an NVIDIA GPU, a cluster over SSH, your own Modal account, or NVIDIA's hosted models with your own key. On Corollary, models such as Boltz-2 run with no hardware or key of your own.
Is Claude Science free?
No. It is included in paid Claude plans, starting with Pro, and is not on the free plan. Verified academic and nonprofit PIs can apply for discounted or free Team seats for a year, while places last.
Can Claude use Corollary?
For finding things, yes: Corollary's MCP server is read-only and lets Claude, or any agent, search our catalogue of models, programs, databases and tasks. Running them happens on Corollary itself, or through the developer API.
Sources
- [1]Claude Science — product page
- [2]Anthropic — Claude Science launch (30 June 2026)
- [3]Claude Science docs — overview
- [4]Claude — pricing
- [5]Claude Science docs — compute providers
- [6]Claude Science docs — tools and environments
- [7]Claude Science docs — core concepts
- [8]Claude Science docs — connectors and skills
- [9]Claude Science docs — how Claude Science works with your data
- [10]Claude Science docs — admin controls
- [11]Claude Science docs — using multiple computers
- [12]Claude — Team plan for scientists
- [13]Claude Science docs — the reviewer
- [14]Claude Science docs — artifacts
- [15]Claude Science docs — remote compute clusters
- [16]Claude Science docs — custom connectors
- [17]Claude Science docs — run on a remote Linux server
Written by Corollary Labs, which makes Corollary — read it with that in mind. Everything said about Claude Science comes from the sources above as they read on 24 October 2026; products change, and if a line here is out of date, write to hello@corollary-labs.com and we will correct it. Claude Science and the other names here are trademarks of their owners, used only to identify their products. Corollary is a non-commercial research demonstrator. It is provided free of charge, without warranty or support, and must not be used for commercial purposes or relied upon for clinical, diagnostic, regulatory or safety-critical decisions.