Antibody & Biologics · AstraZeneca / Prihoda et al.
Germline-guided antibody humanization, validated on clinical-stage molecules.
1–30s
Runs on On-demand GPU
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About this model
Sapiens proposes the minimal set of germline-guided mutations that raise humanness without collapsing affinity. A clinical-stage tool, which matters more than a benchmark number for anything heading toward the clinic.
Standardized I/O contract
Every model in the Hub speaks the same contract, which is what lets the Router and the agent call any of them without special-casing.
Inputs
Heavy chain
Light chain
Outputs
Proposed mutations with humanness delta.
