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SettingsResearch demo · not for clinical or commercial use
Corollary
  1. Catalog
  2. Genomics & Single-Cell
  3. Geneformer

Genomics & Single-Cell · Theodoris et al., Gladstone Institutes

Geneformer

Transformer over 30M transcriptomes for network inference and target prioritisation.

Commercial use permittedThe Apache-2.0 licence allows use in commercial research and products.Apache-2.0
Availability
Not runnable yet

No backend is configured for this model.

Typical latency
7.0min
Credits per run
~2,520
Compute tier
C · Heavy

5–30min

Not runnable yet

This model isn't available to run right now.

Run this model

Geneformer

Needs expression matrix (h5ad url)

About this model

Geneformer learns gene network context from rank-value encoded transcriptomes. Its in-silico deletion analysis is the interesting part: it proposes which genes matter for a disease phenotype without ever running the experiment.

Standardized I/O contract

Every model in the Hub speaks the same contract, which is what lets the Router and the agent call any of them without special-casing.

Inputs

  • matrix_urltext · required

    Expression matrix (h5ad URL)

  • perturb_genestext

    Genes to delete in silico

Outputs

  • rankingtable

    Prioritised genes with shift magnitude.

Specification

Hardware
2× A100
GPU memory
40 GB
Version
2.0
Licence
Apache-2.0
Backend
not configured
MCP server
mcp-genomics-server

Tasks

network inferencegene prioritization
single-cellnetworkstarget-idnature-2023